'Make the impossible possible: Fighting cancer with light and ultrasound"
Baohong Yuan, professor, Bioengineering Department
Abstract: During the past decades, researchers has achieved significant progresses, and now people know more and more about cancers, and developed many advanced diagnostic and treatment technologies. The inspiring news is that cancer death rates fall down 27% in 2019 compared with 1999, according to a CDC report. Of course, fighting with cancer is a long journey since even today cancer is still one of the leading causes of human death worldwide, and people are still facing many challenges to finally win this battle. In this talk, I will introduce some technologies we developed that can be used to potentially improve cancer detection, diagnosis and treatment via light and ultrasound. Specifically, tissue imaging via fluorescence (a type of light) has been widely used for many years because it can provide a lot of unique and important tissue information that other technologies cannot. However, it suffers from either poor spatial resolution or limited imaging depth due to the nature of light. High-resolution fluorescence imaging in deep tissue had been thought impossible before our invention. By using ultrasound to control light, we developed a new technology—ultrasound-switchable fluorescence (USF), and demonstrated how USF overcome the limitations. With the success in developing this technology, we also realized that USF had much more potential applications than what we though initially. I will also give a brief introduction to the potential biomedical applications.
Bio: Dr. Yuan is a professor of bioengineering, Marsha and Bill Carroll Endowed Faculty Fellow, and Distinguished University Professor at UT Arlington. His research is focused on the development of innovative cancer imaging and treatment technologies involved in optical and ultrasound methods. Dr. Yuan has published more than 70 peer-reviewed journal papers, and received/filed/disclosed more than 10 patents. Dr. Yuan has received many grants from Federal, State and local agencies, including NSF (CAREER award), NIH and CPRIT. His major awards include NSF CAREER award, Outstanding Early Career Award, Excellence of Research Award, Outstanding Research Achievement or Creative Accomplishment Award, Kaman Award for Excellence in Research, and Burns Faculty Fellow.
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https://go.uta.edu/research-nov12
Friday, November 12, 2021 at 12:00pm to 1:00pm
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